Welcome to the
Research in our laboratory centers on microelectromechanical systems (MEMS) as applied to biological sensing and manipulation, with an emphasis on controlling, sensing and characterizing biomolecules and cells by integrating MEMS transducers with microfluidics. Our research projects primarily include aptameric microfluidics, implantable MEMS affinity biosensors, MEMS-based characterization of temperature-dependent biomolecular behavior, polymer-enhanced microflow control, and BioMEMS modeling. These projects have resulted in, for example, microfluidic purification systems using thermally controlled, reversible aptamer-target binding; MEMS continuous glucose sensors using viscometric and dielectric affinity assays; MEMS biocalorimeters; compliance-based microflow control devices, and efficient and accurate microfluidic models.
Directions: Our laboratory is located in 170 Engineering Terrace on the Columbia campus, at the southwest corner of 120th Street and Amsterdam Avenue. Detailed directions (including a map) are available for download (PDF, 192 KB).